Fuming Spurs fans sick of ‘Poch Hotspur’ and call for return of Redknapp

first_imgTOTTENHAM supporters fuming with Mauricio Pochettino want to see the Argentine gone – with some even calling for a return of Harry Redknapp instead.Pressure is mounting on the Spurs manager after a horror week in charge.2 A small minority of Tottenham fans want Mauricio Pochettino out – with some calling for Harry Redknapp to returnAfter throwing away a two-goal lead to draw 2-2 at Olympiakos and losing from 1-0 up against Leicester, the Carabao Cup clash at Colchester last night was the perfect chance for Tottenham to get back on track.But a 0-0 draw after 90 minutes meant penalties and following Christian Eriksen and Lucas Moura’s misses, Tom Lapslie converted the winning spot kick to send the League Two side through.Pochettino refused to blame his flops but with 15 defeats in 2019, a small section of Spurs fans have now seen enough.One wrote: “I’d rather redknapp back than wake up and poch is still manager.”Another fumed: “Get Pochettino out of my club.A third added: “Some people out here defending Pochettino. The biggest fraud in world football at the moment. I’m delighted he’s being found out.”ACCA WITH LADBROKES Pick up a whole load of acca features to help you land the big oneOne user tweeted: “Pochettino has wanted to leave Tottenham for 2 years. You can tell. I think he’s p****d he missed out on Real Madrid and United.”The majority of Spurs fans are still content with having Poch in charge and are confident this is merely a blip in form.But five months after one of their greatest nights, the club is descending into crisis with Harry Kane struggling, Daniel Levy’s transfer policy under scrutiny and Poch sulking.In the Argentinian’s five seasons in charge, Spurs have finished fifth, third, second, third and fourth – reaching the Champions League final last term.By comparison, Redknapp led the North Londoners to eighth, fourth, fifth and fourth, getting to the League Cup final and the Champions League quarters.Id rather redknapp back than wake up and poch is still manager.— Daniel Levys Wallet (@AngeSpur) September 24, 2019 Latest Tottenham newsHARRY ALL FOUR ITKane admits Spurs must win EIGHT games to rise into Champions League spotGossipALL GONE PETE TONGVertonghen wanted by host of Italian clubs as long Spurs spell nears endBELOW PARRSpurs suffer blow with Parrott to miss Prem restart after appendix operationPicturedSHIRT STORMNew Spurs 2020/21 home top leaked but angry fans slam silver design as ‘awful”STEP BY STEP’Jose fears for players’ welfare during restart as stars begin ‘pre-season’KAN’T HAVE THATVictor Osimhen keen on Spurs move but only if they sell Kane this summerYOU KAN DO ITKlinsmann quit Spurs to win trophies but says Kane’s better off stayingTURBULENT PAIRINGDrogba and Mido had mid-flight brawl after stewardess prank went wrongAs well as Spurs’ embarrassment, one punter was left ruing what might have been.They backed 20 teams in their £1 accumulator last night, with winnings of more than £13,000 on offer.Teams from England’s non-league divisions, the Austrian Cup and the Argentinian fourth tier all came through but one side didn’t – Tottenham at Colchester.2 Spurs were stunned by their League Two opposition in the Carabao Cup last week to complete a miserable weekCredit: ReutersColchester fans storm onto pitch as they beat Spurs 4-3 on penalties in shock winlast_img read more

Higher BMI at younger age linked to reduced premenopausal breast cancer risk

first_imgThis study was supported by a range of UK, European, and International funders. UK funders included Breast Cancer Now, The Institute of Cancer Research, London, World Cancer Research Fund, Cancer Research UK and the Medical Research Council.Breast Cancer Now thanks principal funder M&S, as well as The Doris Field Charitable Trust and The Liz and Terry Bramall Foundation, for their generous support of the Breast Cancer Now Generations Study. In the largest global study into the relationship between weight and premenopausal breast cancer to date, scientists from The Institute of Cancer Research, London, the University of North Carolina, the US National Institute of Environmental Health Sciences and international collaborators, discovered that increasing premenopausal BMI was linked with a lower risk of the disease and at a greater magnitude than previously suggested.While calling for further studies to uncover the biological mechanisms for this effect, experts have cautioned that being overweight or obese can have many adverse impacts on general health and that after menopause excess body weight increases breast cancer risk – when breast cancer most commonly develops and where obesity remains a leading lifestyle cause of the disease.Leading charity Breast Cancer Now has today urged for women of all ages to be supported to achieve and maintain a healthy weight throughout life, to help reduce their overall risk of cancer and other diseases. The charity has also called for greater investment from governments across the UK to help develop new public health interventions to tackle obesity, amid increasing breast cancer incidence among post-menopausal women.Around 55,000 women are diagnosed with the disease each year in the UK, with nearly 20% of cases developing in women under the age of 50. Previous research has established a link between increased body weight and a decreased risk of breast cancer before the menopause – but due to the lower rates of breast cancer among younger women, past studies had not been large enough to investigate the link in detail or by type of breast cancer.A new analysis of 758,592 women from 19 prospective studies across the world including the Breast Cancer Now Generations Study, found a 12-23% relative breast cancer risk reduction per 5 BMI unit increase (about a 10kg weight increase for women of average height), depending on age.In particular, the team observed that 18-24 year olds in the highest BMI category (a BMI of 30 kg/m2 or more, defined as ‘obese’) were 4.2 times less likely to develop breast cancer before the menopause than those in the lowest BMI category (a BMI of less than 18.5, defined as ‘underweight’).The analysis – led by Dr Minouk Schoemaker and Professor Anthony Swerdlow at The Institute of Cancer Research (ICR, UK), Dr Hazel Nichols at the University of North Carolina (US) and Professor Dale Sandler at the US National Institute of Environmental Health Sciences (NIEHS) – collected information on women’s weights at different ages before following the participants for a median of 9.3 years.A wide range of lifestyle information was also collected from participants to adjust for potential confounding breast cancer risk factors including age at start of menstruation, age at birth of first child and a family history of the disease.The researchers observed that 13,082 out of the 758,592 women went on to develop breast cancer, and found a strong inverse association between BMI and the risk of the disease before the menopause. This applied across the entire weight spectrum, not just among those who were overweight or obese.Related StoriesLiving with advanced breast cancerStudy reveals link between inflammatory diet and colorectal cancer riskNew research links “broken heart syndrome” to cancerThis effect was found to be strongest for BMI at younger adult ages, with a 23% relative risk reduction per five-unit BMI increase for BMI at ages 18-24 – compared with a 12% relative risk reduction per five-unit BMI increase for BMI at ages 45-54.The study observed significant associations between BMI at ages 18-24 and breast cancer risk for both hormone receptor-positive and -negative breast cancer, suggesting that both hormonal and non-hormonal mechanisms may be involved.The study has been published today (Thursday 21th June 2018) in journal JAMA Oncology.Lead author Dr Minouk Schoemaker, Staff Scientist at The Institute of Cancer Research, London, said: Obesity is linked with a higher risk of breast cancer in older women and is one of the leading causes of cancer worldwide. But our study shows that the link with breast cancer is more complicated than we thought, and that younger women with higher BMIs are at lower risk of the disease before the menopause.After the menopause, obese women have an increased risk of breast cancer, which is likely due to oestrogen hormones produced by fat cells. We now need follow-up research to understand why this effect seems to be reversed in younger women.” Baroness Delyth Morgan, Chief Executive at Breast Cancer Now, which helped to fund the research, said: This is the strongest evidence yet that having a higher BMI when you are younger lowers your risk of breast cancer before the menopause. But we must be really clear that weight gain should not be considered an approach to prevent breast cancer.This protective effect is contrary to the situation after the menopause, where excess weight then increases breast cancer risk, where obesity is a leading cause of the disease and where breast cancer is also most common. We’d encourage women of all ages to maintain a healthy weight throughout their life to help lower their overall risk of cancer and other health conditions.We need to understand the biological reasons behind this phenomenon at a molecular level. If we could find a way to mimic the chemical changes in the body in response to body fat that are causing this protective effect, without weight gain being required, it could ultimately lead to a new way to prevent this devastating disease.With more women being diagnosed with breast cancer than ever before, we urgently need renewed focus and funding from UK Governments on promoting sustainable healthy lifestyles to help prevent breast and many other cancers.We’d encourage anyone who is concerned about the impact of their lifestyle on their breast cancer risk to speak to their GP.” Jun 25 2018Having a higher body mass index (BMI) at a younger age is associated with a decreased risk of developing breast cancer before the menopause, major new research funded by Breast Cancer Now and other collaborators has found. Source:http://breastcancernow.org/news-and-blogs/news/higher-bmi-is-associated-with-a-lower-risk-of-breast-cancer-before-the-menopauselast_img read more