This month marks the grand opening of The St. Joe Company’s Village Center at WindMark Beach, a new luxury 2,020 acre residential and resort town, spanning nearly four miles of white-sand beach along the Gulf of Mexico in Northwest Florida. At full build-out, WindMark Beach is planned to include 1,552 units, and much of the property is set aside for conservation and open space.Designed by six of the nation’s most recognized architects, including Margaret McCurry of Tigerman McCurry and John Kirk of Cooper, Robertson & Partners, WindMark Beach is offering a number of new amenities for visitors and buyers starting this month, including:-School of Fish Restaurant, operated by Clark and Blake Brennan, who have created a menu that fittingly features local Gulf Coast seafood with a Creole flair. -Luxury loft homes available for weekly/nightly rental. Select lofts feature floor-to-ceiling windows, and many have balconies with striking Gulf Coast views. All residences are fully furnished and feature stainless steel appliances, granite countertops, a Bose® stereo system, high-speed Internet access and washer and dryer. 19 lofts are currently available; 12 additional lofts will be available to rent in the near future. www.southernresorts.com -The WindMark Beach Club, featuring a large community swimming pool with seamless, beach-style access. The pool is framed by a free form pool deck with a fish-shaped bar surrounded by beautiful green lawn space. The School of Fish Restaurant is providing the pool deck’s food and beverage service. -Public BeachWalk, where one-and-a-half miles of the public three-mile walkway is now complete connecting the community to the stunning beach. A stretch of uninterrupted pathway enables pedestrians, cyclists, roller-bladers and runners to enjoy the stunning views, while making their way along the walkway and miles of meandering footpaths. -Community amphitheater with a sheltered, open-air stage and a sloping green lawn leading down to it; residents and visitors can enjoy concerts, movies and other outdoor venues and local community events. A 1,500 square foot children’s playground area is nearby.WindMark Beach home sites are priced from $99,500 to $546,000 and homes range from $1,095,000 to $1,295,000 million. Homes were designed to capture the essence of vernacular Southern architectural style, with such trademarks as tin roofs, open breezeways, large wood porches. A luxurious WindMark Beach Idea House worth $1 million will be offered in a sweepstakes in August.Visit www.myhomeideas.com/myhome/homegiveaway and www.joe.com/web/TownsAndHomes/WindMarkBeach for more details.
Source:https://www.aip.org/ Jul 4 2018Interstitial fluid transports nutrients and removes waste between the organs and tissues in our body. In the brain, interstitial fluid is thought to be composed of circulating cerebrospinal fluid, cellular waste and blood plasma, and past research has shown a link between interstitial fluid flow and an increased invasion rate of glioblastoma, or brain tumor, cells. A team of biomedical researchers and electrical engineers from the University of Virginia and Virginia Tech recently developed a new method to measure and reconstruct interstitial fluid flow velocities in the brain.This method gives researchers a first look at interstitial fluid flow dynamics in glioma models, and the technique can readily translate to clinical models already using contrast-enhanced magnetic resonance imaging (MRI). The team describes their method in a special issue focusing on the “Bioengineering of Cancer” in APL Bioengineering, by AIP Publishing.Related StoriesMercy Medical Center adds O-arm imaging system to improve spinal surgery resultsNew therapy shows promise in preventing brain damage after traumatic brain injuryAn active brain and body associated with reduced risk of dementiaThe team built on an existing dynamic contrast-enhanced MRI technique that’s already frequently used in clinics to track tumor growth and movement. “We are excited about our technique because we could potentially translate it to patient data that already exists and look at interstitial fluid motion in those patients,” said Jennifer Munson, a lead author on the paper.Munson touted the team’s rigorous validation approach in silico and in vitro. First, the team developed an in vitro model of interstitial fluid flow moving through extracellular space by placing fluid on top of a hydrogel and using MRI to measure how the fluid flowed from top to bottom. Then, they validated their computational model against their experimental measurements.To further validate their technique, Daniel Abler and Russell Rockne, who are co-authors on the paper, created phantom fluid “flow field,” in a computer and then reconstructed that flow using their new imaging methodology. Finally, the team implanted patient-derived glioma cells in mice and examined the mouse tumors using MRI to visualize a real flow field.The team was surprised to find high variability in the flow’s rate and magnitude. “There’s been this classical idea that a tumor develops and there’s this equivalent flow rate going out in all directions like a sphere,” Munson said. “Our method and our visualization approach and modeling show that that’s a large oversimplification and we have a very heterogenous system. Sometimes flow is going out, or in, or along the side.”One day, this technique could potentially help researchers predict how a tumor might grow and, therefore, improve cancer treatments. More immediately, the team plans to use their established method “to understand the relationship between the fluid velocities and the growth of the tumors,” Munson said.