Quick Linkhttps://jobs.nku.edu/postings/8193 Supplemental QuestionsRequired fields are indicated with an asterisk (*). Job Close Date Northern Kentucky University ( NKU ) seeks excellence by enrichingits educational environment and culture through the diversity ofits administration, faculty and staff and by embracinginclusiveness, equity, and global awareness in all dimensions ofits work. NKU is an Equal Opportunity/Equal Access/AffirmativeAction institution. We encourage applications by members of diversegroups and by persons with a demonstrated commitment to issues ofdiversity and experience in achieving goals relative to inclusiveexcellence. Primary Responsibilities Job Open Date05/10/2019 Compensation Title Monday through Friday. Hours per Week19 Is this an internal only posting? Qualifications Duties include performing organic synthesis to make potentialbioactive moleculesAssist research students with lab technique training, experimentsand troubleshootingCompile analyzed NMR spectroscopic data in the requiredformatArrange and submit samples for HRMS testing etc Purpose of Position Working TitleResearch Assistant Commitment to Inclusive Excellence * What is your highest level of education?Bachelor’s degreeMaster’s degree or higher Posting DetailsTo create a Posting, first complete the information on this screen,then click the ‘Next’ button or select the page in the left handnavigation menu. Proceed through all sections completing allnecessary information. To submit the Posting to Human Resources,you must go to the ‘Posting Summary Page’ by clicking on the ‘Next’button until you reach the Posting Summary Page or select PostingSummary Page from the left navigation menu. Once a summary pageappears, hover your mouse over the orange Action button for a listof possible approval step options. Bachelor’s degree in chemistry requiredMust have the ability to create and follow protocols, keep a labnotebook etcMust have basic organic chemistry skills and work with standard labequipment. Minimum EducationBachelor’s Degree Preferred EducationBachelor’s Degree DepartmentChemistry and Biochemistry Months per Year12 Pay GradeN/A Position Number30021750 Salarytbd Minimum ExperienceAcceptable Equivalency Requisition Number2019S1058 Documents Needed to ApplyRequired DocumentsCover Letter/Letter of ApplicationResume/CVReferencesOptional Documents * Do you have research and lab experience?(Open Ended Question) Work Schedule This position is responsible with assisting in research activitiesin the lab, general lab management and equipmenttroubleshooting. Open Until FilledYes Position StatusTemporary
Source:https://www.aip.org/ Jul 4 2018Interstitial fluid transports nutrients and removes waste between the organs and tissues in our body. In the brain, interstitial fluid is thought to be composed of circulating cerebrospinal fluid, cellular waste and blood plasma, and past research has shown a link between interstitial fluid flow and an increased invasion rate of glioblastoma, or brain tumor, cells. A team of biomedical researchers and electrical engineers from the University of Virginia and Virginia Tech recently developed a new method to measure and reconstruct interstitial fluid flow velocities in the brain.This method gives researchers a first look at interstitial fluid flow dynamics in glioma models, and the technique can readily translate to clinical models already using contrast-enhanced magnetic resonance imaging (MRI). The team describes their method in a special issue focusing on the “Bioengineering of Cancer” in APL Bioengineering, by AIP Publishing.Related StoriesMercy Medical Center adds O-arm imaging system to improve spinal surgery resultsNew therapy shows promise in preventing brain damage after traumatic brain injuryAn active brain and body associated with reduced risk of dementiaThe team built on an existing dynamic contrast-enhanced MRI technique that’s already frequently used in clinics to track tumor growth and movement. “We are excited about our technique because we could potentially translate it to patient data that already exists and look at interstitial fluid motion in those patients,” said Jennifer Munson, a lead author on the paper.Munson touted the team’s rigorous validation approach in silico and in vitro. First, the team developed an in vitro model of interstitial fluid flow moving through extracellular space by placing fluid on top of a hydrogel and using MRI to measure how the fluid flowed from top to bottom. Then, they validated their computational model against their experimental measurements.To further validate their technique, Daniel Abler and Russell Rockne, who are co-authors on the paper, created phantom fluid “flow field,” in a computer and then reconstructed that flow using their new imaging methodology. Finally, the team implanted patient-derived glioma cells in mice and examined the mouse tumors using MRI to visualize a real flow field.The team was surprised to find high variability in the flow’s rate and magnitude. “There’s been this classical idea that a tumor develops and there’s this equivalent flow rate going out in all directions like a sphere,” Munson said. “Our method and our visualization approach and modeling show that that’s a large oversimplification and we have a very heterogenous system. Sometimes flow is going out, or in, or along the side.”One day, this technique could potentially help researchers predict how a tumor might grow and, therefore, improve cancer treatments. More immediately, the team plans to use their established method “to understand the relationship between the fluid velocities and the growth of the tumors,” Munson said.